Do you or someone you know have Gout? We are seeking volunteers for a clinical research trial that is studying the efficacy and safety of Methotrexate in combination with Krystexxa to increase response rates in individuals with uncontrolled gout You may qualify for this study if: - You are at least 18 years of age - Have tophi or gouty arthritis or have had more than 2 flares in one year Qualified participants will receive at no cost: - Study medication and study-related health tests - Care from a board certified physician Altoona Arthritis & Osteoporosis Center Altoona Center for Clinical Research 175 Meadowbrpok Lane Duncansvile 800-924-7790 ext. 224 or 814-693-0300 ext. 24 Text: 814-650-0019 www.altoonaarthritis.com No health insurance or referrals required Qualified participants may be reimbursed for time and travel expenses Do you or someone you know have Gout? We are seeking volunteers for a clinical research trial that is studying the efficacy and safety of Methotrexate in combination with Krystexxa to increase response rates in individuals with uncontrolled gout You may qualify for this study if: - You are at least 18 years of age - Have tophi or gouty arthritis or have had more than 2 flares in one year Qualified participants will receive at no cost: - Study medication and study-related health tests - Care from a board certified physician Altoona Arthritis & Osteoporosis Center Altoona Center for Clinical Research 175 Meadowbrpok Lane Duncansvile 800-924-7790 ext. 224 or 814-693-0300 ext. 24 Text: 814-650-0019 www.altoonaarthritis.com No health insurance or referrals required Qualified participants may be reimbursed for time and travel expenses